New Concept For The Treatment Of Implant-related Infections Via Magnetizable Implant Materials Combined With Antibiotic Linkable Magnetic Nanoparticles
نویسندگان
چکیده
Franziska Foth, Nina Angrisani, Peter Behrens, Stephan Schumacher, Anne Christel, Gian Luigi Angrisani, Manfred Kietzmann, Janin Reifenrath. Small Animal Clinic, University of Veterinary Medicine, Hannover, Germany, Institute of Inorganic Chemistry, Leibniz University Hannover, Hannover, Germany, Institute of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine, Hannover, Germany, Institute of Materials Science, Leibniz University Hannover, Hannover, Germany, Institute of of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine, Hannover, Germany.
منابع مشابه
Increased accumulation of magnetic nanoparticles by magnetizable implant materials for the treatment of implant-associated complications
BACKGROUND In orthopaedic surgery, accumulation of agents such as anti-infectives in the bone as target tissue is difficult. The use of magnetic nanoparticles (MNPs) as carriers principally enables their accumulation via an externally applied magnetic field. Magnetizable implants are principally able to increase the strength of an externally applied magnetic field to reach also deep-seated part...
متن کاملImplants modified with polymeric nanofibers coating containing the antibiotic vancomycin
Objective(S): Implant-related infections are disastrous complications in the clinic. One recent strategy to reduce the rate of infection is using the bioactive coating with an antibiotic. The purpose of these bioactive surfaces is to prevent bacterial adhesion to the implant and, consequently, the development of biofilm. In this study, vancomycin-loaded polymeric coating on imp...
متن کاملManagement of a Congenitally Missing Lateral Incisor with Orthodontics, Bone Grafting (a New Method) and Single-Tooth Implant: A Case Report
Careful treatment planning, space management, augmentation of bone and attention to the details of implant surgical and prosthetic techniques are important factors when treating anterior maxilla specially replacement of missing teeth. This case report addresses a chair-side ridge augmentation procedure using autograft bone harvested with trephine drills and placed without using screws and the f...
متن کاملLoading Drug on Nanostructured Ti6Al4V-HA for Implant Applications
Arrayed Ti6Al4V nanotubes (TNT) coated with hydroxyapatite (HA) were synthesized via electrochemical anodization method. Paracetamol was loaded onto TNT-HA electrode. Effects of anodization, nanotube formation and hydroxyapatite deposition on sorption and release of the drug were investigated. Saturation time of paracetamol on the anodized samples was 30% shorter than the hydroxyapatite-coated ...
متن کاملAdipose- Derived Stem Cells as a Tool for Dental Implant Osseointegration: an Experimental Study in the Dog
The biological interaction between the jaw bones and dental implant is fundamental for the long-term success of dental implant placement. Nevertheless, the insufficient bone volume remains a major clinical problem, especially in case of immediate dental implant. Using a canine model, the present study proves the regenerative potential of adipose- derived stem cells (ADSCs) to repair peri-implan...
متن کامل